ACLS and Amiodarone | ACLS-Algorithms.com

Comments

  1. A says

    Hi. May I know what is the normal cumulative dose of amiodarone? At what cumulative dose, it is considered to cause amiodarone pulmonary toxicity

  2. Adel says

    Is it necessary to dilute amiodarone before injection?
    And how much time dose it necessary to push 300mg amiodarone?10 min??
    Thank you

    • ACLS says

      During cardiac arrest amiodarone can be given in 10 mL of the diluent that is used to dilute it or undiluted if it is in the solution form from the vial.

      During cardiac arrest amiodarone is pushed the same way that Epinephrine is pushed (rapidly) and always followed by 20 mL of normal saline.

      Kind regards,
      Jeff

  3. Kelly Gee says

    If ROSC is achieved and patient returns back to VFib arrest. Do we restart the amiodarone algorithm? Meaning do we give another initial dose of 300mg IVP.

    Thank you

    • ACLS says

      There is no clarity in the American Heart Association ACLS guidelines regarding this question. The maximum dose for a 24 hour period is 2.2 g of amiodarone and that would need to be maintained.

      The most likely option here would be for the physician running the code and the team to determine the best option. My guess would be they would probably start off where they had left during the initial code. A second option would be to start at the beginning using 300 mg, but I think this is unlikely.

      Kind regards,
      Jeff

  4. C says

    If a patient achieved ROSC after giving amiodarone 300mg bolus during vfib arrest and are now in a sinus rhythm, are there any situations where you would give a 150mg bolus x10 mins once ROSC is achieved and before starting the maintenance 1mg/min infusion?

    • ACLS says

      There would not be any situation where you would give the bolus unless the person was to go back into cardiac arrest. And as a matter of fact, he would not need to give the post arrest infusion unless there are continued arrhythmias during the post arrest phase.

      Kind regards,
      Jeff

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