ACLS and Adenosine | ACLS-Algorithms.com

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  1. Thiruselvi Subramaniam says

    Is charging on the defib machine and discharging on the patient when it is a pVT or VF accepted ? Saves time I think especially when we say that every second counts and sometimes there is a delay when charging with the paddle on the
    If it is cardioversion it makes sense to charge and discharge on the patient .

    • ACLS says

      Charging should NOT take place until patches/paddles have been placed on the patient. Placement prior to charging is important because safety is important. Charging before pads are placed on the patient increases the risk of accidental early discharge and can result in an electrical arc which can injure the patient and the technician.

      Kind regards,
      Jeff

  2. Kristin m perkins says

    I know this isn’t probably meant for a patient who received this medication. I had Covid in June’20. In the 5 weeks I was sick, my heart rate would take off. 170 bpm +. After several episodes, the last one being over 4 hours long . I went to the ER. They administered this 6mg dosage. The doctor lifted my legs in the air while I was on my back so I was at 90 ° angle. He said it would feel miserable for a few seconds ( it did, nurses and Doc cheered me On to keep breathing) and it dropped my heart rate to 120 bpm.
    Amazing. I was put on a beta blocker, and I am still on it.

  3. Chris says

    Hello
    This website is the only source that I’ve found recommending usage of adenosine in UNSTABLE patients, as an option. While I see it very reasonable, there is no such an option mentioned in ERC or AHA guidelines. There is some evidence for this practice, summarised in BET 1 article. Why, in your opinion, is not this approach included in those big, impactful papers?
    Best regards
    Chris

    • ACLS says

      The reason why I mention it is because the American Heart Association directly in their algorithm provides for the use of adenosine prior to synchronized cardioversion while you prepare for synchronized cardioversion.

      I have never gotten a clear specific answer why they do not cover this in more detail in the book. It’s very strange that they put it right in the algorithm underneath cardioversion in box 4, yet they do not even mention it in the written content.

      It is reasonable, it’s directly on the Tachycardia algorithm in Box 4, and the literature seems to support it so I include it.

      Sorry I couldn’t be more helpful with my answer.

      Kind regards,
      Jeff

    • Christiane Hilker says

      I don’t know. I am guessing and not after my review of some paramedics training manual (LearningExpress) that circumventing the suggestion “I am in control of my mind and body (and environment)”(Learningexpress) is somewhat difficult.

      I appreciate the ability to communicate.

    • ACLS says

      The American Heart Association does not address the use of these two medications within the American Heart Association ACLS protocols.

      Kind regards, Jeff

  4. Astryd says

    I’m guessing Diltiazem was given because maybe when the pt. converted for those short periods of time it was enough to identify the rhythm ? As an Afib/Aflutter? Or because the pt. wouldn’t stay in sinus they wanted to try rate controlling….
    Maybe could not electro-cardiovert because of lack of anticoagulation?

  5. Daniel Lawson says

    Is there a maximum amount of adenosine that can be given to one patient for SVT? In a day or certain amount of time?

    I had a patient who’s SVT wouldn’t stay converted. She got an initial 6 mg. Instead of 12 mg, they did another six. She converted, but then reverted back to SVT. She was than given a 3rd dose of 6 mg and started on diltiazem drip.

    Really not sure why diltiazem was ordered in this situation? She converted for a bit, but then went back into SVT. She was given a 4th 6mg dose of adenosine, and started on Esmolol. Again, the patient converted for a brief time but then reverted back to SVT. Was given a 6th dose of adenosine 6mg, after that the patient was taken to ICU, not sure what happened from there.

    I was completely baffled by the treatment of this patient, I’ve never witnessed so many doses of adenosine given, and all 6 mg doses. Also, I have not seen a diltiazem drip given for SVT.
    The patient was hemodynamically stable throughout, and asymptomatic, so I can understand not cardioverting, but I dont really understand why certain meds were given.

    • ACLS says

      There is not a maximum amount of adenosine that can be given in a period of time. Adenosine is rapidly metabolized within seconds in the body and it is one of the most common molecules that is produced by the body. ATP adenosine triphosphate.

      Every single cell in the body utilizes adenosine and this is why it is so rapidly metabolized.

      Typical doses are 6 mg and 12 mg. I have seen literature that supports the use of 18 mg, but this would be in very rare cases and this can produce prolonged asystole when given as a bolus.

      Kind regards,
      Jeff

  6. ARUN says

    GREETINGS FROM ARUN….

    I AM AN AHA INSTRUCTOR….. STILL SOMANY DOCTORS NOT ACCEPTING THAT ADENOSINE IS THE DRUG OF CHOICE FOR TACHYCARDIAS, THEY ARE RECOMMENDS CARDARONE …I CAN’T UNDERSTAND THAT… CAN U PLEASE VIVID THAT WHY AHA RECOMMENDS ADENOSINE RATHER THAN CARDARONE…..
    REGARDS,
    ARUN (INDIA)

    • ACLS says

      Adenosine is recommended for specific types of tachycardia. Specifically, tachycardia that has an electrical impulse that originates in the atria. SVT and some regular wide-complex monomorphic tachycardia. For these types of tachycardia, adenosine has proved to be more save and effective than cardarone.

      Adenosine is not the medication of choice for VF, and true VT that has its origin of electrical impulse in the ventricles. Cardarone would be preferred and is recommended by the AHA in this case.

      Here are a couple of links that might help:
      Wide Complex Tachycardia

      ECC Guidelines 1

      ECC Guidelines 2

      Kind regards,
      Jeff

  7. Kelli Anderson says

    Some sources indicate the dosing of Adenosine is cut in half if the patient has a central line. Why is this not included in guidelines?

  8. RHONDA STAFFORD says

    IS IT EVER ACCEPTABLE TO GIVE ADENOSINE 18 MG….I WOULD BE REFUSING TO GIVE R/T ACLS GUIDELINES TO NOT COVER US….

    • Jeff with admin. says

      I do not know the reason for delaying the second dose of adenosine for two minutes. I could not find a explanation for this anywhere. The half-life of adenosine is less than 10 seconds and so the adenosine would be completely metabolized within a maximum time of 30 seconds.
      It would seem logical that a second dose could be given after 30-60 seconds, but the guidelines clearly state that it may be repeated after 1-2 minutes.

      Here is the reference from the AHA website: AHA Adenosine

      Kind regards,
      Jeff

    • Jeff with admin. says

      Prior to 2010, the American heart Association guidelines called for the administration of 6 mg, 12 mg, and 12mg.

      After 2010, the 3 dose schedule was dropped for the two doses of 6mg and 12mg.

      I was never able to determine the exact reason for this change, however my assumption was that the third dose of 12 mg was not typically needed and SVT conversion what are usually accomplished with the two initial doses.

      Many providers still include the third dose of 12 mg on the schedule and this is fine. It’s just not included in the American heart Association guidelines any longer.

      Kind regards,
      Jeff

      • Jorge says

        I imagine there is an element of doing the same thing and expecting different results. With the half life being so short, you do not build up a loading dose or therapeutic level so why try the same thing?
        Jorge

      • ACLS says

        There are reports of conversion occurring with the third dose of 12 mg. There are also some physicians that will go up to 18 mg but I have never seen this performed myself. Higher doses can cause prolonged asystole.

        Kind regards,
        Jeff

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